Application Process
In September 1996, Richard P. Bunge, M.D., former director of the Miami Project to Cure Paralysis and a close friend and colleague, died of cancer. In his memory, an annual lectureship was established for the Neuroscience Program at the University of Miami.
Richard P. Bunge, M.D., was at the forefront of research efforts to understand and improve repair processes in the nervous system. In his student days, he discovered that myelin could be broken down and then reformed in the adult mammalian spinal cord, a revolutionary idea in the 1960s. This work led to discovering the mechanism of CNS myelination and the demonstration of the connections between forming myelin and oligodendrocytes. He and his colleagues developed a cell culture system in which myelination could be studied systematically, enabling fundamental discoveries elucidating the process underlying Schwann cell-neuron interactions. These included control of proliferation and the role of Schwann's cell in promoting regeneration of central and peripheral neurons. In 1975, he proposed the idea that cellular grafts, particularly of Schwann cells, could be used to improve repair in the CNS. He pioneered studies of the biology of adult human Schwann cells as a prelude to possible autotransplantation into sites of spinal cord injury in the human. In 1990, he initiated an extensive and detailed characterization of the pathology of human spinal cord injury, which provided novel and fundamental insights into the nature of that injury, including demyelination and axonal degeneration.
After obtaining his M.D. from the University of Wisconsin Medical School in 1960, Richard Bunge went to Columbia University to learn the technique of nerve tissue culture with Dr. Margaret R. Murray, a pioneer in this field. He then held faculty appointments in Anatomy at Columbia University College of Physicians and Surgeons from 1962 to 1970. In Anatomy and Neurobiology at Washington University School of Medicine in St. Louis from 1970 to 1988, before becoming Scientific Director of the Miami Project to Cure Paralysis. While in Miami, The Miami Project gained national recognition within the scientific community as a focused, cohesive center for research related to spinal cord injury. Dr. Bunge held the Kinetic Concepts Distinguished Chair in Neurosurgery. He received numerous honors, including Javits research awards from the NIH, the Friedrich von Rechlinghausen Award for the Advancement of Medical Sciences in Neurofibromatosis, the University of Wisconsin Medical Alumni Association Medicals Alumni Citation, the Gordon Conference of Myelin Chairmans Award, and the prestigious Wakeman Award for his pioneering work in tissue culture and cellular biology of fetal cells, transplantation, and detailed descriptions of human spinal cord injury.
Richard P. Bunge Lecturers
2024 | Nancy Kanwisher, Ph.D. MIT McGovern Institute |
Functional Specializations of the Cortex in Humans: Which, When, and Why? |
2023 | Huda Akil, Ph.D. University of Michigan |
Vulnerability and Resilience to Stress and Depression: Animal models and Human Studies |
2022 | Eric Nestler, M.D., Ph.D. Dean/Director, Friedman Brain Institute |
Transcriptional and Epigenetic Mechanisms of Drug Addiction |
2021 |
King-Wai Yau, Ph.D. |
Light Detection in the Eye – The Big Picture |
2020 | Michael Petrides, Ph.D. McGill University |
Neuronal Circuits for Language Processing |
2019 | Edvard Moser, Ph.D. Norwegian University of Science and Technology |
Space and Time in the Brain |
2018 | Connie Cepko, Ph.D. Harvard Medical School |
Cell Fate Determination in the Retina and Preservation of Cone Survival |
2017 | Marc Tessier-Lavigne, Ph.D. Bing Presidential Professor, President, Stanford University |
Sculpting Neuronal Connections: The Logic and Mechanisms of Axon Growth and Pruning |
2016 | Martin Chalfie, Ph.D. University Professor, Department of Biological Sciences, Columbia University |
Determining Neuronal Fate in C. elegans |
2015 | Dr. Ehud Isacoff University of California, Berkeley |
CNS Light-Gated Neurotransmitter Receptors: From Molecular Mechanism to Circuit Function |
2014 | Dr. Robin Franklin Wellcome Trust - MRC Cambridge Stem Cell Institute |
CNS Remyelination: From Mechanisms to Medicines |
2013 | Dr. Lawrence Wrabetz University at Buffalo, The State University of New York |
Pathogenesis in Hereditary Demyelinating Neuropathies: Toxic Mechanisms Target Development |
2012 | Dr. Jeremy Brockes University College London, School of Life and Medical Sciences |
The Nerve Dependence of Vertebrate Limb Regeneration |
2011 | Dr. Chien-Ping Ko University of Southern California |
Synapse-Glia Interactions in the Neuromuscular System |
2010 | Dr. Marianne Bronner-Fraser California Institute of Technology |
Gene Regulatory Network Governing Neural Crest Formation |
2008 | Dr. James L. Salzer New York University Smilow Research Center |
Axo-Glial Interactions that Direct Assembly of Myelinated Nerves |
2007 | Dr. William Snider University of North Carolina School of Medicine |
Dissection of Neurotrophin Signaling Pathways by Mouse Genetics |
2006 | Dr. Lynn Landmesser Case Western Reserve University |
Novel Roles of NCAM Isoforms in Synaptic Maturation and Function |
2005 | Dr. Rita Balice-Gordon University of Pennsylvania School of Medicine |
Mechanisms Underlying Synaptogenesis: Insights from Mice and Zebrafish |
2004 | Dr. Wes Thompson University of Texas |
Using Transgenics to Examine the Role of Schwann Cells at the Neuromuscular Junction |
2003 | Dr. Eugene M. Johnson, Jr. Washington University in St. Louis School of Medicine |
Trophic Factor Deprivation-Induced Neuronal Death |
2002 | Dr. Jeff Lichtman Washington University in St. Louis |
Monitoring Synapses in Flourescent Mice |
2001 | Dr. Mu Ming Poo UC Berkeley |
Mechanisms in Axon Guidance |
2000 | Dr. David R. Colman Mount Sinai School of Medicine |
Common Cell Adhesion Molecules of Myelin and the CNS Synapse: Structure, Evolution, and Function |
1999 | Dr. Thomas M. Jessell Columbia University |
The Molecular Control of Motor Neuron Identity and Connectivity |
1998 | Dr. Joshua Sanes Washington University in St. Louis |
Genetic Analysis of Synapse Formation in Mice |
1997 | Dr. Gerald D. Fischbach Washington University in St. Louis |
Neuregulin Regulation of Synapses and Glia |