Our research seeks to understand how biological systems function as integrated networks, rather than isolated parts and exploit this knowledge to disrupt or repair pathologies.
Mapping, Modeling and Reimagining Biological Systems
Using both experimental and computational approaches, our investigators study how genes, proteins, and cells interact to produce complex behaviors, and how those interactions can be modeled, predicted, and, ultimately, engineered.
The department’s research strengths include:
- Systems-level analysis: Using and developing quantitative mathematical models to understand how molecular interactions give rise to cellular and organismal function.
- Cellular and molecular mechanisms: Investigating the pathways that regulate cell behavior, signaling, and communication.
- Synthetic and quantitative biology: Building and testing new biological systems to uncover the principles that govern life’s adaptability.
- Translational discovery: Applying systems-based insights to identify new therapeutic targets and strategies.
By fostering creativity, interdisciplinary thinking, and bold scientific exploration, the Department of Cell and Systems Biology is advancing a new era of research that connects mechanism with medicine and imagination with impact.