Toll-Like Receptor-Mediated Activation of Unfolded Protein Response and Inhibition of Baff Chromatin Remodeling Complexes Targets Chondrosarcoma. K. Galoian, V. Dahl, B. Becker, C.Denny, A. Sedani, A.Perez, A. Moran, A.Hoyt , J.Brown. Sylvester Annual Retreat 2021
Moran A, Hoyt, Sedani ,A Granger C; Prettel JM.; Conway, S . and Galoian K .Can PRP- 1 receptors or its ligand serve as diagnostic biomarker between benign enchondroma and low grade human chondrosarcoma. Florida Orthopedic Society, Orlando, FL, 2019.
Hoyt A, Moran,A ,Granger,C Saigh,S Sedani ,A and Galoian, K.A PRP-1Eliminates ALDHhigh cancer stem cell population and regulates aberrant Wnt/β-catenin pathway in human JJ012 chondrosarcoma cells. Orthopedic Research Society, Meeting , Austin, Texas 2019.
Granger CJ, Moran A, Hoyt AK, Saigh S, and Galoian K.A Proline rich polypeptide-1(PRP-1) inhibits cancer stem cell anchorage independent growth and spheroid formation in human chondrosarcoma. Florida Orthopedic Society, Orlando, FL, 2019.
Galoian K, , Moran,A, Saigh S ,Hoyt, A, Greif D Abstract ID: 2993194: Inhibition of embryonic stem cell markers expression by PRP_1 leads to elimination of cancer stem cell population in human chondrosarcoma CTOS, 2018, November, Rome, Italy.
Galoian,K (corresponding author) Qureshi, A, Patel,P Moran , A Abstract ID:2992803 Innate immunity toll lie receptors TLR1/2, TLR6 AND MUCIN MUC5B are binding partners with antiproliferative peptide PRP-1 in human chondrosarcoma CTOS, 2018, November, Rome, Italy.
Galoian K, Luo S, Qureshi A, Patel P, Price R, Morse A, H.T Temple.Effect of cytostatic PRP-1 on tumor repressors of inflammatory pathway and IL6 mediated signaling in chondrosarcoma. SCCC retreat , Miami, Fl March 3-4, 2017
Galoian K, Luo S, Qureshi A, Price,R ,Morse,A.S, Temple H.T. Effect of cytostatic PRP-1 on tumor suppressors of inflammatory pathway and IL6 mediated signaling in chondrosarcoma. 21st Annual Connective Tissue Oncology Society meeting , Lisbon, Portugal, November 9-12 (poster session 1)(Tumors-GIST), 2016.
Presented also at Orthopaedic Research Society meeting, Orlando, Florida, November 5-8, 2016.
Galoian K., Luo S, Qureshi A, Price,R ,Morse, A.S, Temple H.T. Effect of cytostatic prp-1 on socs3 and interleukin 6 mediated inflammatory signaling in chondrosarcoma Miami Winter symposium (Nature Elsevier , University of Miami,) Hyatt Regency 24-28 January, 2016.
Galoian K, et al,: Epigenetic regulation of embryonic stem cell marker mir302c in human chondrosarcoma as determinant of antiproliferative activity of proline rich polypeptide 1 and Treatment with a small molecule IDH1 inhibitor suppresses tumorigenic activity and decreases production of the oncometabolite 2-hydroxyglutarate in IDH1- mutant human chondro-sarcoma cells” AACR Basic Science of sarcoma conference and CTOS, November 3-8, Salt Lake City, Utah 2015.
Karina Galoian, PhD, Toumy Guettouche, Biju Issac, Amir Qureshi, H. T. Temple Regulation of onco and tumor suppressor miRNAS by MTORC1 inhibitor PRP-1 un human chondrosarcoma, (poster) Miami Winter Symposium 2015, (UM and Elseviers Publishers) January Towards Personalized Medicine.
Karina Galoian, PhD, Amir Qureshi, MD, H. T. Temple, MD Targeting Cancer Stem Cell Marker miR302C in Human Chondrosarcoma Determines the Antiproliferative Activity of Proline Rich Polypeptide 1 Cancer Tumors POSTER #:1946 ORS Annual Meeting, March 28-31. Las Vegas, Nevada, 2015.
Luyuan Li, AnnaPaz Mejia, Britt Johnson, Karina Galoian, PhD., Breelyn A. Wilky, MD, Andrew E. Rosenberg, Olaf Bodamer, Jonathan C. Trent. Evaluation of IDH mutation, IDH 1 inhibition and 2-hydroxyglutarate in human chondrosarcoma cell lines and patients plasma. CTOS meeting, October 15-18, 2014, Berlin, Germany.
Karina Galoian, PhD, Toumy Guettouche, Biju Issac, Amir Qureshi, H.T. Temple Regulation of onco and tumor suppressor miRNAS by MTORC1 inhibitor PRP-1 un human chondrosarcoma. CTOS meeting, October 15-18, 2014, Berlin, Germany.
Galoian, K.A, T. Guettouche, B.Issac ,L. Navarro and H.T. Temple. Lost miRNA surveillance of Notch, IGFR pathway- road to sarcomagenesis.Tumor Biology, 2013 Accepted, 18th CTOS annual meeting New York City, USA.
Galoian, K.A, Temple HT. ECM-cell adhesion independent drug resistance in chondrosarcoma is mediated by GSK3beta inactivation Combined CTOS/MSTS Meeting, Chicago, IL, October 26-29, 2011.
Galoian, K.A, Temple H.T, Galoyan A.A. Cytostatic effect of the hypothalamic cytokine PRP-1 is mediated by its inhibition of mTOR and cMyc in high grade metastatic chondrosarcoma. 16th Meeting of Connective Tissue Oncology Society, Paris, France, 2010.
Galoian, K.A, Scully S.P, Galoyan A.A Antitumorigenic properties of hypothalamic PRP-1 peptide in chondrosarcoma. 15th Meeting of Connective Tissue Oncology Society meeting, Miami Beach , FL, 2009; and Miami Winter Symposium Targeting Cancer Invasion and Metastasis, Miami Beach, FL, 2010.
Galoian, K.A, Garamszegi N, Garamszegi S, and Scully S. Molecular Mechanism of Tenascin C -1 Invasive Potential on Matrix Metalloproteinase -1 invasive potential. 14th Meeting of Connective Tissue Oncology Society meeting, London, UK, November 13-15, 2008.