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Sylvester's Brain Tumor Institute Research

Department of Neurological Surgery

Some of the most common forms of brain cancer are the most malignant. Today, physicians are often able to improve a patient’s life expectancy and their quality of life, but are not able to offer a cure. Since most brain tumors are genetically different, understanding the genetics and drug sensitivity of each individual brain tumor surgically removed from the patient is crucial to personalized therapy.

Based on the information gleaned from these studies, combination treatments and clinical trials will be initiated to provide individualized treatment. This approach is innovative as it provides rapid analysis of a particular patient’s drug sensitivity, which will directly translate into therapeutic treatment plans and results.

Researchers from the Sylvester Brain Tumor Institute pose for a group photo
From left to right: Antonio Iavarone, M.D., Macarena de la Fuente, M.D., Anna Lasorella, M.D., Ricardo Komotar, M.D.

Our team closely collaborates with medical school colleagues in areas of cancer neuroscience, genomics, pharmacology, physiology, and neurology.

Here, we are training the next generation of specialists in our field, by offering fellowships in brain tumors, neuropathology, and neurosurgery.

Translational Research

As a research facility committed to creating and integrating new knowledge, we offer our patients the opportunity to participate in clinical trials of promising and novel drugs and therapies. Our comprehensive Brain Tumor Institute offers each patient the opportunity to participate in our tissue bank and tumor registry. This program benefits both our current patients and future patients, by expanding our understanding of brain tumors, refining and finding new treatments, providing hope and increasing quality of life.

Clinical Trials

Our team guides and participates in clinical trials that translate innovative and cutting-edge therapies into active, open protocols accessible to patients. We are proud to offer neuro-oncologic clinical trials that center on immune-modulated tumor therapy via vaccine administration, radiation sensitizers, and surgical adjuncts.

For more information on the Brain Tumor Institute, click here.