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Frontotemporal Dementia Research (FTD)

Approximately 5% of all dementia patients present with Frontotemporal Dementia (FTD), including ~10-20% of those dementia patients before the age of 65 years. Though FTD is unique in its loss of social cognition or language disturbances, it shows overlap with other diseases, such as Alzheimer Disease (AD).

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Information on genetic factors contributing to disease can help in diagnosis, prognosis and eventually development of treatments. The vast majority of genetic research in FTD so far has been done patients of European descent. As for Alzheimer disease, genes driving the disease risk for FTD may differ between different ancestries. Furthermore, several clinical therapy trials currently ongoing for FTD are based on genetic findings identified in European ancestry only.

We are looking to enroll all individuals of the wider South Florida population who have a diagnosis of either behavioral FTD or language variant FTD/primary progressive aphasia. A special interest goes out to those patients with other family members with any dementia diagnosis.

University of Miami Principal Investigators

  • Karen Nuytemans, Ph.D.
  • Margaret Pericak-Vance, Ph.D.

For more information, or to participate in our Frontotemporal Dementia Study, please contact us at:

Anisley Martinez, M.D.
Clinical Research Coordinator
Phone: 305-243-2569
Email: FTD-HIHG@miami.edu