Xiaoyu Jiang, M.D.

Roles

• Biography

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  Published our data in high impact journals, such as Blood and Nature Communications. Established very strong relationships with our collaborators. Personally, I possess extensive research experience, which includes 3 years of successful product development experience in a leading bio-engineering company in China.
  
  I also have expertise on multidisciplinary research areas, such as bioengineering, biochemistry, molecular biology, protein science, immunology, and cancer biology. I have participated in many and varied research projects including NIH R01s. I have received funds as Principal Investigator and co-Investigator and demonstrated a record of accomplished research with grants, patents, papers, and medicine product.

• Education & Training

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  Education

  2002: Sun Yat-sen University

  PhD, Biochemistry and Molecular Biology

  1999: Central China Normal University

  MS, Entomology

  1992: Hubei Normal College

  BS, Biology

  Post Graduate Training

  2008: University of Miami

  Post-Doctoral Fellowship

• Honors & Awards

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  No result found

  
  

• Research Interests

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  Human Germinal center Associated Lymphoma (HGAL) is associated with prolonged survival of diffuse large B cell lymphoma and classical Hodgkin’s disease patients. We have successfully revealed HGAL’s function in B cells and B cell lymphoma, specifically, its role in B cell signaling, antigen internalization and cell motility.
  
  Currently, we further extend our research to understand HGAL’s underlying molecular mechanism. HGAL functions as an adaptor protein; its binding motifs, together with its partners and their sub-cellular locations, determine the signaling specificity; thus, HGAL is positioned to regulate cell signaling in a spatial and temporal fashion. Traditional biochemistry tools with pools of cells cannot address HGAL’s spatiotemporal signaling, so we developed and validated new tools, methods, and animal models for successfully examining HGAL’s mechanism.

• Publications

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• Copyrights & Patents

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  Method for preparing recombined thymosin alpha 1 Publication number: CN1661037 A

  236179511296, 2005

  Open Reading Frame (ORF) Phage Display Publication number: US8754013 B2

  236179509248, 2014