Roles
- Professor
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Biography
Dr. Varan Govind is a tenured Professor in the Department of Radiology at the University of Miami Miller School of Medicine. An internationally recognized expert in advanced magnetic resonance spectroscopy (MRS), diffusion imaging, and multimodal neuroimaging, Dr. Govind has built a distinguished career advancing imaging biomarkers for neurological disease, neurotrauma, and infectious disease.
Dr. Govind earned his Ph.D. in Electrical and Computer Engineering from the Indian Institute of Technology, Kanpur, following his master’s and bachelor’s degrees in physics from the University of Madras. He began his research career at the All India Institute of Medical Sciences in New Delhi before moving to the University of California, San Francisco, where he spent five years as a postgraduate researcher and assistant specialist in radiology. In 2002, he joined the University of Miami, rising through the academic ranks from Research Assistant Professor to tenured Professor in 2020.
Over the past three decades, Dr. Govind has authored or co-authored more than 150 peer-reviewed publications, book chapters, and invited reviews. His scholarship has appeared in leading journals including Journal of Neurotrauma, Journal of Neuroimaging, Neuroradiology Journal, Frontiers in Neuroscience, and NMR in Biomedicine. His contributions to seminal reference works, such as the Handbook of Magnetic Resonance Spectroscopy In Vivo and Magnetic Resonance Spectroscopy of Degenerative Brain Diseases, reflect his international reputation in the field.
His research program emphasizes the development and application of whole-brain MR spectroscopic imaging, diffusion tensor and kurtosis imaging, and multimodal MRI techniques. Dr. Govind’s work has yielded important insights into the structural and biochemical changes underlying amyotrophic lateral sclerosis, traumatic brain injury, Alzheimer’s disease, HIV-associated neurocognitive disorders, and pediatric brain development after prenatal exposures. More recently, he has played a central role in collaborative investigations of HIV, substance use, and neuroinflammation, including multi-institutional projects funded by the NIH and international consortia.
Dr. Govind has served as principal investigator and co-investigator on numerous federally funded grants, including projects supported by the NIH, NIDA, and the Miami Center for AIDS Research. His work has advanced translational applications of neuroimaging to improve diagnosis, monitor treatment, and guide interventions for vulnerable patient populations.
In addition to his research, Dr. Govind is a dedicated educator and mentor. He has supervised graduate students, postdoctoral fellows, and junior faculty, many of whom have gone on to establish successful research careers. He is also an active reviewer for leading journals in radiology, neuroscience, and biomedical imaging, and he regularly presents his work at international conferences such as ISMRM, ASNR, and the Research Society on Alcohol.
Through his career-long dedication to advancing imaging science, Dr. Govind has made enduring contributions to radiology, neuroscience, and translational medicine. His research continues to shape the field of neuroimaging and to strengthen the University of Miami’s position as a leader in radiologic innovation and discovery. -
Education & Training
Education
Post Graduate Training
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Honors & Awards
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Publications
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Clinical Trials
Viewing 0 of 4 clinical trials.
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In this project, we will implement innovations to extend use of Contingency Management (CM) to facilitate alcohol use abstention among people living with HIV (PLWH). We will address feasibility concerns in community health centers and clinics. Our approach to extending CM will use mobile health, alcohol biosensors, and gamification to engage participants through social connections and friendly competition.
- Principal Investigator: Varan Govind
- Study Phase: N/A
- Enrollment Status: Open
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The objective for this project is to determine what health functions change in persons with heavy drinking when they stop (or reduce) drinking for 30 days
- Principal Investigator: Varan Govind
- Study Phase: N/A
- Enrollment Status: Closed
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Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease of motor neurons, affecting both upper motor neurons (UMN) (the motor cortex and corticospinal tracts (CST)) and lower motor neurons (LMN) (the brain stem and spinal cord). LMN involvement in ALS can be determined objectively using electromyography and muscle testing; however, radiologically determining UMN involvement in ALS patients is timeconsuming and usually neuroimaging methods are used for eliminating the presence of other diseases/disorders that mimic ALS. In addition, sensitive biochemical markers that are specific to ALS are yet to be identified. So, currently UMN ALS is diagnosed solely based on subjective clinical assessments. The objective of this study is to use noninvasive and nondestructive wholebrain magnetic resonance techniques, namely, proton magnetic resonance spectroscopic imaging (MRSI) and diffusion tensor imaging (DTI), and evaluate their usefulness in quantifying neurochemical and microstructural changes in subjects with ALS. By combining wholebrain neurochemical and structural changes data, this study will improve the ability to identify potential markers for diagnosing UMN functional status with possibly higher specificity and sensitivity. The specific aims of this study and the hypotheses to be tested are: 1) To characterize cerebral chemical and structural abnormalities in the corticospinal tracts of subjects with amyotrophic lateral sclerosis. Hypothesis 1: The concentrations of NAA and CHO from the motor cortex and multiple individual locations along and integrated over the CST will be altered in subjects with ALS as compared to these concentrations from control subjects. The degree and the spatial extent of these alterations will correlate with the UMN function measures.Hypothesis 2: The white matter structural integrity of the CST, measured at multiple anatomical locations, will show reduced diffusion anisotropy in subjects with ALS as compared to that of control subjects, and the change in diffusion anisotropy and its spatial extent will correlate with the UMN function measures.Hypothesis 3: Multiparametric analysis that incorporates neurochemical and structural information from the motor cortex and the CST, as measured by MRSI and DTI, respectively, will have a greater association with the clinical assessments of the UMN function measures than with the individual measure.2) To explore metabolite and structural changes in the nonmotor brain regions of subjects with amyotrophic lateral sclerosis.This exploratory aim will evaluate metabolite and structural changes in nonmotor brain regions, including frontal lobe white matter, in the wholebrain MRSI and DTI data, and their association with clinical and neuropsychological assessments. It is hypothesized that the neuroimaging measures will enable differentiation of subgroups of ALS subjects, with and without frontotemporal dementia, thereby improving specificity and guiding clinical treatment.
- Principal Investigator: Varan Govind
- Study Phase: N/A
- Enrollment Status: Closed
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We are interested in improving the physical and cognitive health of heavy drinkers by using a probiotic supplement and stimulating the nervous system using a portable non-invasive stimulation device.
- Principal Investigator: Varan Govind
- Study Phase: N/A
- Enrollment Status: Open
