Roles
Professor of Cell Biology
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Biography
Dr. Rotundo is a cell biologist whose research focuses on acetylcholinesterase (AChE), an important component of the neuromuscular junction and all cholinergic synapses in the central and peripheral nervous systems.
Our laboratory focuses on the regulation of neurotransmission via the enzyme, acetyl cholinesterase. We study: 1) The contributions of protein folding and assembly in regulating active molecules at synapses. 2) The development of novel probes for identifying cholinergic synapses. 3) RNA binding proteins that control protein translation at muscle and neuronal synapses in response to specific signals. 4) The repair of neuromuscular and CNS cholinergic synapse following acetylcholinesterase inactivation. -
Education & Training
Education
Post Graduate Training
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Honors & Awards
No result found
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Research Interests
Biogenesis, folding, and trafficking of acetylcholinesterase, the enzyme that terminates cholinergic neurotransmission in nervous systems. -
Publications
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