Roles
Research Associate Professor
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Biography
Perturbations in molecular homeostasis form the basis of many human diseases. Understanding the mechanism can provide novel targets for intervention. It is difficult to obtain diseased human pancreatic tissue for laboratory investigations. Therefore, development of experimental models of the disease is important. Using these experimental models including those developed by our group, we are studying pathophysiological mechanism of acute and chronic pancreatitis. My current investigations are focused on understanding the mechanisms of local pancreatic inflammation becoming systemic. For understanding the role and contributions of inflammation in pancreatic cancer, we are using genetically engineered mice models. With basic background in Biochemistry and extensive experience of experimental pancreatitis research, I find myself ideally suited for the role. Teaching has been my other passion. Training next generation of investigators is important and I continue to train post-doctoral fellows for studying the disease mechanism using experimental models of pancreatitis. -
Education & Training
Education
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Honors & Awards
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Teaching Interests
For many years, I have done classroom based teaching. My current focus is on training post-doctoral fellows in generation of experimental models of pancreatitis and investigating the disease mechanism. -
Research Interests
Dr. Darwa's research focuses on acute and chronic pancreatitis. This involves understanding the mechanism of the disease and evaluation of the potential therapeutics using experimental models of the disease. Another area of interest is to understand the role of chronic pancreatic inflammation in promoting pancreatic cancer. -
Publications
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