Understanding the intricacies of deregulated signaling networks as the pathophysiological basis underlying tumorigenesis, cancer progression, and metastatic dissemination is at the core of my research interests. These studies emphasize the role of Rho small GTPases and oncogenic kinases in clinically relevant models with translational applicability.
My research projects overarch key disarranged nodal signaling pathways leading to molecular aberrancies in hormone-mediated and oncogenic-driven epithelial-derived solid tumors, including human adrenocortical, breast, prostate cancer, and lung adenocarcinoma.
The integrative goal is to identify emergent molecular targets and pave the way for novel pharmacological approaches and pioneering strategies to reshape the spectrum of therapeutic venues, aiding the advancement of translational and precision medicine.
