Dr. De la Fuente's research focuses on clinical and translational research in primary human brain tumors with a goal to develop innovative, more effective treatments as well as develop radiographic biomarkers to better assess the efficacy of those treatments. This effort has been conducted along two tracks 1) Optimizing therapy for patients with low- and high-grade glioma using a combined approach of targeted therapies and or immunotherapy, and 2) developing molecular imaging through collaborations with basic research scientists. Dr. De la Fuente has a strong interest in gliomas and metabolic pathway alterations, particularly isocitrate dehydrogenase (IDH) mutations. Her work has been specifically focused on IDH inhibitors for the treatment of IDH mutant gliomas as well as the identification and clinical application novel radiographic biomarkers for IDH mutant gliomas. Dr. De la Fuente is currently leading and collaborating in multiple active research projects with colleagues from Neurosurgery, Radiology, Medicine, Pediatrics, Medical Physics, and Radiation Oncology. Dr. De la Fuente is a Memorial Sloan Kettering trained neuro-oncologist serving as principal investigator for several clinical trials, including IISs, as well as collaborations within NIH-funded cooperative groups and industry.
Dr. De la Fuente is deeply interested and invested in achieving diversity, equity, and inclusion (DEI) in the academic medical environment. As part of this commitment, she currently serves as one of the co-chairs of the Women and Diversity Committee of the Society for Neuro-Oncology (SNO) and as the Equity Focused Clinical Investigator (EfCI) for University of Miami to North American Star Consortium (NASC).