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Shehadeh Lina

Lina Shehadeh, Ph.D.

Department:

Medicine

Division:

Cardiovascular Medicine

Shehadeh Lina

Roles

  • Research Professor
  • Biography

    Dr. Shehadeh is active in biomedical education research with a focus on integrating compassion and cultural competence. She is exploring the intersection of AI and biomedical research and education, developing innovative approaches to democratize quality educational content creation and collaborative learning platforms using no-code AI tools.
  • Education & Training

    Education

    • 2002
      Florida Atlantic University, Boca Raton, FL
      PhD, Complex Systems and Brian Sciences
    • 1997
      Florida Atlantic University, Boca Raton, FL
      Other, Teaching Sciences
    • 1995
      Florida Atlantic University , Boca Raton, FL
      BS, Microbiology
  • Honors & Awards

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    • Research Interests

      Dr. Shehadeh’s laboratory is investigating the molecular mechanisms by which microRNAs regulate atherogenesis and stem cell differentiation. Dr. Shehadeh’s expertise in computational biology and data mining allows her to compile masses of genomic datasets to identify candidate genes and microRNAs with potential therapeutic functions. Dr. Shehadeh has recently identified a microRNA that reduces serum cholesterol levels and atherosclerotic burden in a mouse model of atherosclerosis (APOE-/-). Her team is currently running studies to identify mechanism of action including regulation of smooth muscle cell plasticity. Dr. Shehadeh has also identified a microRNA that regulates mesenchymal stem cell differentiation. Her lab is currently investigating the mechanisms by which bone-marrow derived stem cells are pushed into adipogenic lineage and away from osteogenic lineage, via a single microRNA molecule. In parallel with the mechanistic studies, the Shehadeh lab is actively engaged in developing a targeted delivery method for microRNAs using aptamer technology.
    • Publications

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      • Copyrights & Patents

      • Professional Activities

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        Articles & News