Contact
Research/Lab Website
Roles
Research Professor
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Biography
Dr. Dave received his PhD in Biochemistry in 2000 from the M. S. University of Baroda, India. During his PhD training he worked on several research projects including secondary complications of diabetes, Alzheimer’s disease and drug toxicity among others. From 1999 to 2000 Dr. Dave served at the Zandu Pharmaceutical Works, Mumbai, India, as a Biochemist, where he participated in a drug development program. Dr. Dave completed his post-doc training under the mentorship of Dr. Miguel Perez-Pinzon. -
Education & Training
Education
Post Graduate Training
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Honors & Awards
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Research Interests
Dr. Dave's research focuses on various aspects of cerebral ischemia and hemorrhagic stroke.
Diabetes and stroke Cerebral ischemia and heart disease are the most serious complications of diabetes, accounting for more than 84% of the mortality among diabetics. Epidemiological studies of cerebral ischemia suggest that diabetes both increases the risk of incidence and exacerbates the consequences of cerebral ischemia. Our research aims to understand the mechanisms by which diabetes increases the risk of cerebral ischemia and also cerebral ischemic damage.
Hemorrhagic stroke Despite being the cause of significant morbidity and mortality, spontaneous intracerebral hemorrhage (sICH) remains the least treatable stroke subtype. The prevention of hematoma expansion in sICH is an attractive therapeutic target. Currently, we are evaluating a novel strategy to limit hematoma expansion in a rodent model of sICH.
Tobacco and spontaneous intracerebral hemorrhagic Smoking is one of the main risk factors for spontaneous intracerebral hemorrhage (sICH): the deadliest subtype of stroke. However, the effect of smoking on outcomes following sICH is not known. The goal of this project is to determine the effect of chronic nicotine exposure on outcomes following sICH. -
Publications
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Professional Activities
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