Contact
Roles
Professor and Chair
-
Biography
Dr. Kirill Martemyanov is a neuroscientist and pharmacologist whose career bridges academic leadership, scientific discovery, and entrepreneurial innovation. An expert in neuronal signaling, GPCR pharmacology, and drug discovery, Dr. Martemyanov has collaborated extensively with biotechnology and pharmaceutical companies. His laboratory investigates the function and physiological significance of G protein-coupled receptors (GPCRs) in the nervous system, exploring their roles across a range of systems and neuronal circuits.
His research focuses on uncovering mechanisms underlying neuropsychiatric diseases, addiction, vision, motor control, and reward behavior. Using unbiased genetic and proteomic approaches, his lab identifies new components of GPCR signaling cascades and regulatory networks. This work integrates multiple levels of analysis, from molecular structures and optical sensors to genetic mouse models, ultimately translating fundamental discoveries into potential therapeutic advances.
A significant focus of recent work involves orphan GPCRs, elucidating their functions in the nervous system and developing molecular probes to study them. In addition to his academic pursuits, Dr. Martemyanov is committed to transforming basic scientific discoveries into real-world applications. As the co-founder of two biotechnology companies, he is leading efforts to develop novel drugs targeting serious brain disorders, including depression and opioid addiction. -
Education & Training
Education
Post Graduate Training
-
Honors & Awards
No result found
-
Research Interests
The main focus of Dr. Martemyanov’s research is the fundamental principles that regulate signaling via G protein coupled receptors (GPCR). GPCRs mediate a vast variety of critical biological processes ranging from proliferation and motility to cellular reception and excitability. GPCR signaling pathways are of particular importance for the nervous system function where they control many fundamental processes including excitability, differentiation, sensory perception and synaptic transmission. Importantly, but not surprisingly, even subtle imbalances in GPCR signaling often lead to the most profound nervous system disorders ranging from blindness and cognitive problems to grave neurological diseases. -
Publications
Disclaimer: The information presented in this section has been consolidated using AI and machine learning technologies. While every effort has been made to ensure accuracy, errors may occur. If you identify any inaccuracies, please use this link to inform our data team. Your feedback is greatly appreciated and helps us improve the quality of our content.