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Jonathan

Jonathan Harry Schatz, M.D.

Department:

Medicine

Division:

Hematology

Jonathan

Contact

Lab: 305-243-7742
Research/Lab Website

Roles

  • Professor of Clinical Medicine

  • Biography

    Jonathan Schatz, M.D., is a Professor of Clinical Medicine and Chair of the CMSR Scientific Advisory Committee in the Division of Hematology at the University of Miami Miller School of Medicine. He began his career as a journalist after graduating from the University of Wisconsin-Madison before pursuing science and medicine. After premedical studies at Brandeis University, he earned his medical degree from the University of Chicago Pritzker School of Medicine, conducting research on blood cancer–related genes in the laboratory of Dr. Harinder Singh. He completed an internal medicine residency at University of Chicago Hospitals and a hematology-oncology fellowship at Memorial Sloan Kettering Cancer Center, where he focused on lymphoma research.

    Dr. Schatz began his faculty career at the University of Arizona in 2012, establishing an independent laboratory studying treatment resistance and novel therapies for lymphomas while maintaining an active clinical practice. In 2015, he joined Sylvester Comprehensive Cancer Center at the University of Miami, where his research focuses on overcoming resistance mechanisms to targeted therapies. His work identified PIM kinase–mediated maintenance of cap-dependent translation as a resistance mechanism to mTOR inhibitors and has led to novel therapeutic strategies, including targeting the DEAD-box RNA helicase eIF4A with rocaglates now entering clinical trials.

    The Schatz laboratory focuses on diffuse large B-cell lymphoma (DLBCL), exploring novel combination therapies, mechanisms of recurrent oncogenes such as BCL10, and druggable dependencies including Cyclin-G Associated Kinase (GAK). The lab also investigates tumor-intrinsic factors influencing responses to cellular immunotherapies, including CAR T-cell therapies, with ongoing efforts to translate these findings into clinical applications.

  • Education & Training

    Education

    • 2004
      University of Chicago Pritzker School of Medicine
      MD

    Post Graduate Training

    • 2010
      Memorial Sloan-Kettering Cancer Center
      Fellowship, Hematology/Oncology
    • 2007
      University of Chicago Hospitals
      Residency, Internal Medicine

    Licensures and Certifications

    • Florida Medical License (ME 124599)

    • American Board of Internal Medicine

      Medical Oncology

    • American Board of Internal Medicine

      Internal Medicine

  • Honors & Awards

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    • Research Interests

      Non-Hodgkin lymphoma, Translation, Cancer Immunotherapy, Drug Discovery

    • Publications

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        Disclaimer: Information presented in this section has been consolidated using AI and machine learning technologies. While every effort has been made to ensure accuracy, errors may occur. If you identify any inaccuracies, use this link to inform our data team. Your feedback is appreciated and helps us improve the quality of our content.

      • Professional Activities

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        Articles & News

        Disclaimer: Information presented in this section has been consolidated using AI and machine learning technologies. While every effort has been made to ensure accuracy, errors may occur. If you identify any inaccuracies, use this link to inform our data team. Your feedback is appreciated and helps us improve the quality of our content.

        Clinical Trials

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