Roles
Assistant Professor of Clinical
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Biography
John Michael Bryant, M.D., is an Assistant Professor in the Department of Radiation Oncology at the University of Miami Miller School of Medicine and an affiliate member of the Sylvester Comprehensive Cancer Center. A Miami native, Dr. Bryant specializes in the treatment of gastrointestinal and thoracic malignancies, integrating advanced radiation therapy approaches, including MRI-guided adaptive radiotherapy, to deliver precise, individualized care.
Dr. Bryant’s research sits at the intersection of engineering, physics, and radiation oncology. With formal training in electrical engineering and doctoral training in biomedical engineering, he leads translational efforts to develop magnetoelectric nanoparticles (MENPs) as tumor-targeted theranostic agents that combine diagnostic imaging with remotely activated, localized therapy. In parallel, he collaborates on machine learning and deep neural network applications to support response assessment, outcome prediction, and real-time treatment adaptation for anatomically complex tumors.
Dr. Bryant earned his M.D. from the Herbert Wertheim College of Medicine at Florida International University and completed his radiation oncology residency at the H. Lee Moffitt Cancer Center & Research Institute/University of South Florida (serving as Chief Resident). He has authored numerous peer-reviewed publications and has received internal and external research support. His work includes the first in vivo demonstration of magnetoelectric nanoparticles (MENPs) in a preclinical pancreatic cancer model, enabling MRI-based tumor localization and remotely activated, targeted therapy. -
Education & Training
Education
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Teaching Interests
Dr. Bryant is committed to teaching and mentorship across the medical and engineering education continuum, with a particular focus on resident and fellow education in radiation oncology and multidisciplinary cancer care. His teaching interests include:
Resident and fellow education in clinical radiation oncology (GI and thoracic malignancies), including contouring, treatment planning, and on-treatment management. MRI-guided adaptive radiotherapy and other precision radiation techniques for anatomically complex tumors. Leadership development, emotional intelligence, and team-based communication in oncology training (including multidisciplinary journal club leadership).Translational science education that bridges engineering/physics principles with clinical implementation in radiation oncology. Mentorship of medical students, residents, and graduate trainees pursuing physician-scientist and clinician-engineer pathways. -
Research Interests
Dr. Bryant’s research integrates nanotechnology, advanced imaging, and computational methods to enable more adaptive and personalized cancer care. Key areas of interest include:
Magnetoelectric nanoparticles (MENPs) and related nanotechnologies for tumor-targeted theranostics, including MRI-based localization and remotely activated therapy.MRI-guided adaptive radiotherapy (MRgART) and high-dose, hypofractionated/ablative approaches for GI and thoracic malignancies. Radiomics and delta-radiomics for response assessment and outcomes prediction in radiation oncology. Machine learning and deep neural networks to support real-time treatment adaptation and decision support. Translation of precision radiation therapy techniques to challenging and anatomically complex tumor sites. -
Publications
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