Dr. Guest is a neurosurgeon scientist with a multi-disciplinary interest in spinal cord medicine, especially spinal cord injury and myelopathy. Recovery-targeted therapeutics have tested repair, neuroprotection, and neuromodulation. Programs have been translated from in vitro and preclinical studies through Phase 1-3. Dr. Guest has been developing clinical trials with both academic and industry sponsors, writing applications for regulatory submission, patents, and providing guidance to several organizations. In clinical practice, Dr. Guest has a strong interest in neurophysiology as a tool to assess spontaneous and therapeutics-promoted recovery. Dr. Guest enjoys serving as a member of the grants review panel for the California Institute for Regenerative Medicine because of the diversity of medical conditions and exciting evolution of stem cell, gene editing, and gene therapy applications that are reviewed.