Roles
Research Assistant Professor | Computational Biologist
-
Biography
Dr. Fulvio D’Angelo is a Research Assistant Professor in the Department of Neurological Surgery at the University of Miami Miller School of Medicine and a member of the Sylvester Comprehensive Cancer Center. He applies his expertise in cancer genetics and computational biology to advance research on nervous system tumors, with a focus on their molecular heterogeneity and evolution. His research leverages single-cell genomics and integrative analyses to uncover how tumor ecosystems shape disease progression and therapy resistance.
Dr. D’Angelo earned his PhD in Genetics from the University of Naples Federico II, Italy, and completed his post-doctoral fellowship at Columbia University in New York.
HIs research led to the generation of the first genomic and epigenomic landscape of NF-1 glioma, published in Nature Medicine (D’Angelo et al., 2019), that provided foundational insights into NF-1 research and glioma biology. Building on this foundation, his current research aims to dissect tumor–immune interactions and identify molecular drivers of treatment resistance. -
Education & Training
Education
Post Graduate Training
-
Research Interests
Dr. Fulvio D'Angelo's research investigates the genetic and epigenetic drivers of glioma, including those associated with Neurofibromatosis type 1 (NF-1), a genetic disorder that predisposes individuals to tumors of the nervous system. By integrating laboratory-based methods with computational biology, Dr. D’Angelo aims to uncover how glioma evolve, interact with the immune microenvironment, and resist therapy—ultimately informing new therapeutic strategies for brain cancer. His most recent work on glioblastoma investigates tumor heterogeneity and genetic clonal evolution, providing insight into the functional mechanisms of treatment resistance and informing future therapeutic strategies. -
Publications
Disclaimer: The information presented in this section has been consolidated using AI and machine learning technologies. While every effort has been made to ensure accuracy, errors may occur. If you identify any inaccuracies, please use this link to inform our data team. Your feedback is greatly appreciated and helps us improve the quality of our content.