Professor, Department of Psychiatry & Behavioral Sciences, Neurology
Director, Cognitive Neurosciences and Aging (CNSA)
Associate Director of the Florida Alzheimer’s Disease Research Center
Director of the UM Clinical Core
Biography
Dr. Loewenstein Loewenstein has had continuous NIH grant funding for over 30 years. He is Principal Investigator on several large NIH and state funded grants and has a number of ongoing longitudinal investigations nationally and internationally with new cognitive instruments developed in his laboratory. The Direct Assessment of Functional status Scale (DAFS) was one of the first performance-based scales for Alzheimer’s disease and has been translated into multiple languages. The Semantic Interference Test (SIT) and the Loewenstein- Acevedo Scales for Semantic Interference and Learning (LASSI-L) have shown considerable promise in the early detection and prediction of progression in patients with early Alzheimer’s disease and other neurodegenerative disorders. Susceptibility to proactive semantic interference (PSI) and most importantly, the failure to recover from semantic interference (frPSI) are extremely sensitive markers of preclinical AD, progression over time and brain biomarkers of amyloid load, tau load, cortical thickness and brain volumetric loss. Dr. Loewenstein and colleagues have recently made discoveries in the the the areas of failures of inhibitory control and unbinding of previously learned semantic associations. Dr. Loewenstein’s directs the Center for Cognitive Neuroscience and Aging and works with many departments across the UM and numerous medical schools and Universities across the United States and abroad.
Education & Training
Education
1986: Florida State University, Florida
PhD, Clinical Psychology
1983: Florida State University, Florida
MS, Clinical Psychology
1981: University of South Florida, Florida
BA, Psychology
Licensures and Certifications
American Psychological Association-American Board of Professional Psychology
Board Certified in Clinical Neuropsychology
Teaching Interests
Dr. Loewenstein has mentored many post-doctoral fellows in neuropsychology and numerous PhD and MD residents in numerous disciplines. His laboratory is committed to training the next generation of leaders is the study of the brain, novel cognitive challenge tests, state-of- the science neuroimaging and other biomarkers to detect incipient Alzheimer's disease and related disorders.
Research Interests
Dr. Loewenstein has a number of research interests centering on the early detection of early cognitive impairment in neurodegenerative and other brain disorders, development of novel cognitive and functional measures, examining relationships between neuropsychological measures and neuroimaging and other biomarkers of early Alzheimer’s disease. Further, Dr. Loewenstein and other investigators in his laboratory have been involved in developing cognitive and functional interventions for normal elderly patients as well as those with Alzheimer’s disease (AD) and related disorders and development of culture fair assessment instruments.
Publications
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