Roles
- Associate Professor of Clinical Pediatrics
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Education & Training
Education
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Publications
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Clinical Trials
Viewing 0 of 3 clinical trials.
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The purpose of this study is to evaluate the safety and efficacy of a single dose of ex vivo base edited, autologous CD34+ human hematopoietic stem and progenitor cells (HSPCs) inpatients with severe SCD. The product is called BEAM-101. It causes deletion in the participant's genes allowing hemoglobin F to increase. An increase in hemoglobin F may make the participant's sickle cell disease milder or may cure it.
- Principal Investigator: David Crawford
- Study Phase: Phase I/II
- Enrollment Status: Not Accepting
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A Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units Manufactured by the National Cord Blood Program and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult Patients
- Principal Investigator: David Crawford
- Study Phase: Phase 2
- Enrollment Status: Closed
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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients With Hematologic Malignancies and Other Indications
- Principal Investigator: David Crawford
- Study Phase: Phase IV
- Enrollment Status: Closed