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David Coffey

David Coffey, M.D.

Department:

Medicine

Division:

Myeloma

David Coffey
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Roles

  • Assistant Professor of Clinical Medicine
  • Co-Leader for the Computational Oncology Research Lab in the Myeloma Institute
  • Biography

    David Coffey, M.D., is an Assistant Professor of Medicine in the Division of Myeloma at the University of Miami’s Sylvester Comprehensive Cancer Center. His research focuses on developing precision medicine tools for multiple myeloma by translating genomic assays into clinically actionable insights. With expertise in computational oncology, data science, and machine learning, he studies tumor biology in the context of the immune microenvironment. His prior research has leveraged single-cell profiling, immune receptor sequencing, genomic analyses, and ex vivo drug testing to uncover immune responses, mechanisms of resistance, and predictors of therapeutic outcome.
  • Education & Training

    Education

    • 2009
      University of Colorado, Denver, CO
      MD, Medicine
    • 2003
      Tulane University, New Orleans, LA
      BS, Ecology and Evolutionary Biology

    Post Graduate Training

    • 2015
      Fred Hutchinson Cancer Center, Seattle, WA
      Fellowship, Hematology/Oncology
    • 2012
      University of Colorado Denver, Denver, CO
      Residency, Internal Medicine

    Licensures and Certifications

    • Florida Board of Medicine

      Medical Doctor
    • American Board of Internal Medicine

      Medical Oncology
    • American Board of Internal Medicine

      Internal Medicine
  • Honors & Awards

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    • Research Interests

      David Coffey, M.D. is a computational oncologist specializing in the study and treatment multiple myeloma, a blood cancer affecting the antibody-producing plasma cells. His research investigates how multiple myeloma cancer cells interact with the body’s immune system. By utilizing advanced multi-omic single-cell analyses of the immune system alongside DNA sequencing of tumor cells, he aims to uncover why the immune system may sometimes fail to stop myeloma from progressing. Through this work, Dr. Coffey seeks to identify innovative strategies to empower the immune system to eliminate myeloma more effectively.
    • Publications

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      • Professional Activities

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        Articles & News