Roles
- Research Professor
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Biography
Born in Italy, Daniela Frasca graduated from the University of Rome “La Sapienza” with a BSc University degree in Biology cum laude in May 1980. In 2009, she received her PhD from the University of Rome “La Sapienza” for studies performed in the Department of Microbiology and Immunology at the University of Miami Miller School of Medicine. In January 2010 she became Research Assistant Professor, in February 2020 Research Associate Professor, and in June 2026 Research Professor in the Department of Microbiology and Immunology. Since 2023, she is Visiting Professor at the Department of Microbiology, Immunology and Parasitology, UNIFESP, Federal University of São Paulo, Brazil. -
Education & Training
Education
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Honors & Awards
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Teaching Interests
After the success of the MIC 460 and of the MIC 775 classes, my goal is to continue teaching these classes in which motivated students participate with great interest in joining my research
topics. -
Research Interests
One major focus of Dr. Frasca’s research has been the characterization of the defects in humoral immunity observed in individuals with inflammatory conditions (aging and obesity) and diseases (Type-2 Diabetes, Rheumatoid Arthritis and Breast Cancer). These are associated with increased serum inflammation, intrinsic B cell inflammation and chronic immune activation, all leading to dysfunctional B cell responses, i.e. decreased secretion of protective antibodies to infections and vaccines and increased secretion of pathogenic autoimmune antibodies. This strongly depends on the composition, as well as on the metabolic profile of the B cell pool, with higher frequencies of pro-inflammatory B cell subsets, which are characterized by a hyper-metabolic phenotype needed to support secretion of inflammatory markers and of pathogenic autoimmune antibodies.
Full list of my published work is available at
https://www.ncbi.nlm.nih.gov/myncbi/daniela.frasca.2/bibliography/public/ -
Publications
Disclaimer: Information presented in this section has been consolidated using AI and machine learning technologies. While every effort has been made to ensure accuracy, errors may occur. If you identify any inaccuracies, use this link to inform our data team. Your feedback is appreciated and helps us improve the quality of our content.Professional Activities
Articles & News
HIV and Aging: Evaluating Metabolic Deficits and Immune Dysfunction
Miller School Study Highlights Role of Immunometabolism in Aging
New Miller School Study Highlights How Obesity Hinders COVID-19 Immune System Response
Disclaimer:
Information presented in this section has been consolidated using AI and machine learning technologies. While every effort has been made to ensure accuracy, errors may occur. If you identify any inaccuracies, use this link to inform our data team. Your feedback is appreciated and helps us improve the quality of our content.