Roles
Research Assistant Professor, Dr. John T. Macdonald Foundation Department of Human Genetics
Head of the Genetic Epidemiology Division in the Center for Genetic Epidemiology and Statistical Genetics (CGESG)
-
Biography
Dr. Kunkle is a genetic epidemiologist whose research primarily focuses on investigating the genetic factors involved in the development of Alzheimer’s Disease (AD). His studies apply a combination of genomic, epidemiology and biostatistical techniques to large-scale genome-wide genotyping and sequencing datasets. He is an Assistant Professor in the Dr. John T. Macdonald Foundation Department of Human Genetics and Director of the Genetic Epidemiology Division in the Center for Genetic Epidemiology and Statistical Genetics (CGESG) at the John P. Hussman Institute for Human Genomics (HIHG).
He is a principal investigator (PI) of several grants including 1) the multi-PI National Institutes on Aging (NIA) U19 “Recruitment and Retention for Alzheimer’s Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)” (http://www.readd-adsp.org/) which aims to build a resource that greatly expands Alzheimer’s disease genetic studies in currently underrepresented African ancestry populations and Hispanic/Latino groups, 2) the multi-PI NIA R01 “Integrative Genomic Approaches for Understanding Sex Differences in Alzheimer's Disease”, which is investigating sex-specific factors for AD, and 3) the multi-PI NIA U01 “Additional Sequencing for the Alzheimer's Disease Sequencing Project (ADSP)", which as part of the ADSP-Follow-Up-Study (FUS), aims to reveal the genomic architecture of AD across ancestrally diverse populations.
Dr. Kunkle also helps to lead analyses for several large multi-site studies of Alzheimer’s including: 1) the ADSP, the largest Alzheimer’s sequencing project, where he serves on the Gene Verification Committee and as co-chair of the ADSP-FUS Sequencing Work Group; 2) the Alzheimer’s Disease Genetics Consortium (ADGC), a collaborative network in the United States that includes the 29 Alzheimer Disease Research Centers (ADRCs) funded by the NIA; and 3) the International Genomics of Alzheimer’s Project (IGAP), the largest international Alzheimer’s consortium. This work has led to key research findings including numerous novel genetic loci involved in the development of Alzheimer’s Disease. -
Education & Training
Education
Licensures and Certifications
-
Honors & Awards
No result found
-
Publications
Disclaimer: The information presented in this section has been consolidated using AI and machine learning technologies. While every effort has been made to ensure accuracy, errors may occur. If you identify any inaccuracies, please use this link to inform our data team. Your feedback is greatly appreciated and helps us improve the quality of our content.
-
Professional Activities
No result found