Roles
- Professor of Biochemistry and Molecular Biology
- Director, Precision Medicine Initiative
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Biography
Catholic University School of Medicine, Rome, Italy MD 1982 Medicine
Catholic University School of Medicine, Rome, Italy Post grad 1990-92
Pediatric OncologyCatholic
University School of Medicine, Rome, Italy Residency 1982-86 Hematology
Catholic University School of Medicine, Rome, Italy Residency 1986-90 Pediatrics
Brain Tumor Research Ctr., UCSF, San Francisco Res. Fellow 12/90-8/94 Oncology -
Education & Training
Education
Post Graduate Training
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Honors & Awards
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Teaching Interests
May main teaching interest resides in contribute to the formation of future independent scientists through my mentorship of pre-doctoral students and post-doctoral scientists, sharing knowledge and skills, overseeing my trainee’s work, helping them to make contact with other researchers and assisting with career counseling. Each of these aspect is important for attracting and retaining diverse talents and to break down barriers to encourage the scientific pursuits of women and underrepresented groups. -
Research Interests
My research focuses on the link between stem/progenitor cells and cancer stem cells in the nervous system. Our work generated transformative knowledge on the role of cell fate determination factors, such as ID proteins, in brain tumor development and maintenance and characterized, using molecular definition, the normal and oncogenic functions of these factors. Furthermore, we successfully pioneered the use of high throughput genomic technologies in the search for actionable lesions in glioblastoma, leading to translation into clinical trials for patients with FGFR-TACC positive glioblastoma and other cancer types that harbor this same gene fusion. With a background in clinical oncology, I am interested in trans-disciplinary approaches combining data science and computational pharmacology to develop an experimentally validated pipeline for personalized cancer therapeutics. Towards this goal, which represents an exciting and complementary part of my research program, I have secured federal funds and partnerships that led to novel clinical interventions for brain tumors. -
Publications
Disclaimer: Information presented in this section has been consolidated using AI and machine learning technologies. While every effort has been made to ensure accuracy, errors may occur. If you identify any inaccuracies, use this link to inform our data team. Your feedback is appreciated and helps us improve the quality of our content.Copyrights & Patents
Professional Activities
Articles & News
How Team Science at Sylvester is Changing Brain Cancer Care
How Scientists at Sylvester are Learning to Outrun Cancer Resistance
Tracking a Shape-Shifting Cancer: How IDH-Mutant Gliomas Evolve After Treatment
Disclaimer:
Information presented in this section has been consolidated using AI and machine learning technologies. While every effort has been made to ensure accuracy, errors may occur. If you identify any inaccuracies, use this link to inform our data team. Your feedback is appreciated and helps us improve the quality of our content.