Roles
Professor of Otolaryngology, Neurosurgery, Pediatrics and Biomedical Engineering
-
Biography
Dr. Adrien Eshraghi is a tenured professor of Otolaryngology, Neurosurgery, Pediatrics, and Biomedical engineering. He serves as the Director of the Hearing Research and cochlear implant Laboratory, the Co-Director of the University of Miami Ear Institute, and the Vice-speaker of the Medical Faculty Council at the University of Miami Miller School of Medicine. He is a surgeon-scientist with over 150 scientific papers published, mainly focused on cochlear implant surgery and various hearing disorders. -
Education & Training
Education
Licensures and Certifications
-
Teaching Interests
Dr. Eshraghi is enthusiastically involved in mentoring undergraduate and medical students, visiting scholars, residents, as well as national and international scholars. They have the opportunity of learning in clinics, observe surgeries, and volunteer in his Hearing Research Laboratory. -
Research Interests
Dr. Adrien Eshraghi is a surgeon-scientist with a special interest in cochlear implants and hearing disorders. One major focus of his research is to understand the molecular mechanisms underlying loss of residual hearing following cochlear implantation and to develop effective therapies to protect this residual hearing. He has conducted research into the evaluation of macroscopic damage to the inner ear following cochlear implantation, and the grading system he proposed for this is now widely used by the international scientific community. He is now exploring the molecular mechanisms involved in sensory cell death that can lead to the loss of residual hearing. Parallel to investigating these mechanisms, he is also focused on developing and testing novel otoprotective and regenerative therapies, including novel drugs, targeted drug therapies with nanoparticles, therapeutic hypothermia, and stem cell therapy. These inner ear treatment modalities will potentially help patients suffering from hearing loss, tinnitus or dizziness.
He is also a Professor in the Departments of Neurological Surgery and Biomedical Engineering, and in this role, he carries out research on neurological disorders, most notably Autism Spectrum Disorders (ASD). He sees many ASD patients that are referred for the evaluation of communication disorders, such as hearing loss, speech delay, and central auditory processing disorders (CAPD), and performs cochlear implants in these patients to improve auditory outcomes when necessary. His team is actively developing experimental models of ASD and CAPD to provide insights into the pathophysiology of these neurological disorders and guide the development of novel treatment modalities. Presently he and his team are utilizing genome editing techniques such as CRISPR/Cas9 as well as neurons derived from induced pluripotent stem cells (iPSC) from ASD patients to understand the molecular mechanisms underlying this neurodevelopmental disorder.
In addition to translational laboratory research, his efforts are also directed at clinical studies. He is conducting clinical research in various complex cases of cochlear implant surgery such as patients having dual diagnosis of hearing loss and autism, cerebral palsy, cytomegalovirus infection, Usher Syndrome, inner ear abnormalities, or revision cochlear implant surgery. He is actively conducting clinical trials in patients with hearing loss, tinnitus, and dizziness. -
Publications
Disclaimer: The information presented in this section has been consolidated using AI and machine learning technologies. While every effort has been made to ensure accuracy, errors may occur. If you identify any inaccuracies, please use this link to inform our data team. Your feedback is greatly appreciated and helps us improve the quality of our content.