Agenda Miller School of Medicine

2027 Agenda

Time	Session
8:00 - 8:30	Registration + Coffee
8:30 - 8:40	Welcoming Remarks Nima Sharifi, M.D.
Session 1: Regulation of Human Metabolism
8:40 - 9:30	Expanding Indications and Mechanisms for GLP-1 Medicines Daniel Drucker, M.D.
9:30 - 10:00	TBD Speaker Coming Soon
10:00 - 10:30	Morning Break
10:30 - 11:00	The impact of the environment on human metabolism Matthew Vander Heiden, M.D., Ph.D.
11:00 - 11:30	New methods of chemoproteomics to elucidate oxysterol biochemistry and metabolism Alison Ondrus, Ph.D.
11:30 - 1:00	Lunch
Session 2: Steroid Metabolism in Cancer and Human Disease
1:00 - 1:30	Origins of 11-oxygenated androgens and race Richard Auchus, M.D., Ph.D.
1:30 - 2:00	What do 11-oxygenated androgens mean for clinical outcomes in prostate cancer? Bruce Montgomery, M.D.
2:00 - 2:30	TBD Nima Sharifi, M.D.
2:30 - 3:00	Social isolation, glucocorticoid receptor and metabolism in breast cancer Suzanne Conzen, M.D.
3:00 - 3:30	Afternoon Break
Session 3: Lifestyle Interventions and Metabolic Reprogramming
3:30 - 4:00	TBD Speaker Coming Soon
4:00 - 4:30	The Case for Diet as an Adjunct Therapy to Enhance the Gut Microbiome and Oncologic Treatment Outcomes Carrie Daniel-MacDougall, Ph.D.
4:30 - 5:00	Dietary interventions and metabolic modifications Tracy Crane, Ph.D.
5:00	Closing Remarks Nima Sharifi, M.D.
5:00 - 8:00	Poster Session and Reception

Past Agendas

2026

+ –

Time	Session
8:00 - 8:30	Registration + Coffee
8:30 - 8:40	Welcoming Remarks Nima Sharifi, M.D.
Session 1: Metabolic Interventions in Human Health and Disease
8:40 - 9:30	Interventional Cardiac Metabolic Pathophysiology Zoltan Pierre Arany, M.D., Ph.D.
9:30 - 10:00	Ketogenic Fasting Interventions in Prostate Cancer Laura Sena, M.D., Ph.D.
10:00 - 10:30	Morning Break
10:30 - 11:00	Fatty Acid Synthase Inhibition Clinical Studies in Prostate Cancer Massimo Loda, M.D.
11:00 - 11:30	Metabolic Health and Prostate Cancer Survivorship Alicia Morgans, M.D., M.P.H.
11:30 - 1:00	Lunch
Session 2: Prostate Cancer Metabolism
1:00 - 1:30	Androgen Production, Uptake, and Conversion Enzymes in CRPC Charles Ryan, M.D.
1:30 - 2:00	Alternative Androgen Synthesis Pathways in Prostate Cancer Nima Sharifi, M.D.
2:00 - 2:30	Pyruvate Kinase is a Therapeutic Target in Prostate Cancer Daniel Schmidt, M.D., Ph.D.
2:30 - 3:00	A Stress-Adaptive Lipid Kinase Axis Defines Metabolic Vulnerabilities in Neuroendocrine Prostate Cancer Yuanyuan Qiao, Ph.D.
3:00 - 3:30	Afternoon Break
Session 3: Metabolic Mechanisms and Approaches
3:30 - 4:00	Targeting Metabolism in Prostate Cancer Shaun Stauffer, Ph.D.
4:00 - 4:30	Dark GPCRs and Mitochondrial Transport Daniel Isom, Ph.D.
4:30 - 5:00	Ketone-body Dependent Post Translational Modifications Zhipeng Wang, Ph.D.
5:00	Closing Remarks Nima Sharifi, M.D.
5:00 - 8:00	Poster Session and Reception

2025

+ –

Time	Session
8:00 AM - 8:30 AM	Coffee and Registration
Session 1: Metabolism in Human Health and Disease
8:30 AM - 8:45 AM	Welcoming remarks Nima Sharifi, M.D.
8:45 AM - 9:30 AM	Mitochondrial Dynamics and Cardiometabolic Disease Dale Abel, M.D., Ph.D.
9:30 AM - 10:00 AM	Insulin Regulation of Bile Acid Physiology Rebecca Haeusler, Ph.D.
10:00 AM - 10:30 AM	Morning Break
10:30 AM - 11:00 AM	Metformin Intervention in STAMPEDE Silke Gillessen, M.D.
11:00 AM - 11:30 PM	Human Steroid Metabolism Phenotypes Nima Sharifi, M.D.
11:30 PM - 12:00 PM	Muscle Metabolic Alterations with Physical Activity and Disuse Blake Rasmussen, Ph.D.
12:00 PM - 1:30 PM	Lunch
Session 2: Dietary Interventions to Combat Metabolic Dysfunction
1:30 PM - 2:00 PM	Dietary Interventions and Nutrient Availability in Cancer Progression Evan Lien, Ph.D.
2:00 PM - 2:30 PM	Nutritional Strategies to Improve Metabolic Health and Potentially Longevity Eric Ravussin, Ph.D.
2:30 PM - 3:00 PM	A ketone shunt generates anti-obesity ketone metabolites Maria Dolores Moya Garzon, Ph.D.
3:00 PM - 3:30 PM	Afternoon Break
Session 3: Approaches for Studying Human Metabolism
3:30 PM - 4:00 PM	Spatial Imaging of Metabolites Paired with Transcript and Peptide Imaging Erin Seeley, Ph.D.
4:00 PM - 4:30 PM	Toward Single Cell Resolution for Mass Spectrometry Metabolite Imaging Jens Soltwisch, Ph.D.
4:30 PM - 5:00 PM	Physiomimetic Microsystems for Studying Metabolism Ashutosh Agarwal, Ph.D.
5:00 PM - 8:00 PM	Poster Session & Reception

2024

+ –

Time	Session
7:30 AM - 8:00 AM	Coffee & Registration
8:00 AM - 8:15 AM	Welcoming Remarks Nima Sharifi, University of Miami
Session 1: Normal Metabolism and the Diversity of Human Metabolic Phenotypes
8:15 AM - 10:15 AM	Overarching Perspectives on Metabolism Ralph DeBerardinis, Howard Hughes Medical Institute, UT Southwestern Opportunities for Studying Diverse Populations in Miami Brandon Mahal, University of Miami Prostate Cancer and Genetic Ancestry in Jamaican Men Chad Ritch, University of Miami
10:15 AM - 10:45 AM	Morning Break
Session 2: What Happens When Metabolism Goes Awry?
10:45 AM - 12:30 PM	Metabolic Adverse Effects of Hormonal Therapy Alicia Morgans, Dana-Farber Cancer Institute, Harvard Medical School Metabolic Stress in Men Training for the Special Forces Harris Lieberman, Department of Defense Effects of Stress and Hormonal Therapy on Steroid Metabolism Nima Sharifi, University of Miami
12:30 PM - 1:30 PM	Lunch
Session 3: How Can We Favorably Modify Human Metabolism?
1:30 PM - 3:30 PM	Time Restricted Eating as a Method to Optimize Metabolism Satchidananda Panda, Salk Institute Mechanistic Consequences of Amino Acid Deprivation on Translation Alicia Darnell, Massachusetts Institute of Technology Dietary Interventions with Cancer Therapy Marcus Goncalves, Weill Cornell Medicine Regulation of an Exercise-Inducible Appetite Suppressant Shuke Xiao, Stanford University
3:30 PM - 4:00 PM	Afternoon Break
Session 4: Approaches for the Study of Human Metabolism
4:00 PM - 6:00 PM	Spatial Resolution of Carbohydrate Metabolism Ramon Sun, University of Florida Imaging Metabolic Dependence of the Myc Oncogene Peter Kreuzaler, University of Cologne Molecular Mapping at Cellular Resolution with Multimodal Imaging Mass Spectrometry Jeffrey Spraggins, Vanderbilt University Emerging Approaches for the Study of Metabolomics in Humans Gary Patti, Washington University
6:00 PM	Closing Remarks and Adjourn
Evening	Cocktail Social

Agenda

2027 Agenda

Welcoming Remarks

Session 1: Regulation of Human Metabolism

Expanding Indications and Mechanisms for GLP-1 Medicines

TBD

The impact of the environment on human metabolism

New methods of chemoproteomics to elucidate oxysterol biochemistry and metabolism

Session 2: Steroid Metabolism in Cancer and Human Disease

Origins of 11-oxygenated androgens and race

What do 11-oxygenated androgens mean for clinical outcomes in prostate cancer?

TBD

Social isolation, glucocorticoid receptor and metabolism in breast cancer

Session 3: Lifestyle Interventions and Metabolic Reprogramming

TBD

The Case for Diet as an Adjunct Therapy to Enhance the Gut Microbiome and Oncologic Treatment Outcomes

Dietary interventions and metabolic modifications

Closing Remarks

Past Agendas

2026

Welcoming Remarks

Session 1: Metabolic Interventions in Human Health and Disease

Interventional Cardiac Metabolic Pathophysiology

Ketogenic Fasting Interventions in Prostate Cancer

Fatty Acid Synthase Inhibition Clinical Studies in Prostate Cancer

Metabolic Health and Prostate Cancer Survivorship

Session 2: Prostate Cancer Metabolism

Androgen Production, Uptake, and Conversion Enzymes in CRPC

Alternative Androgen Synthesis Pathways in Prostate Cancer

Pyruvate Kinase is a Therapeutic Target in Prostate Cancer

A Stress-Adaptive Lipid Kinase Axis Defines Metabolic Vulnerabilities in Neuroendocrine Prostate Cancer

Session 3: Metabolic Mechanisms and Approaches

Targeting Metabolism in Prostate Cancer

Dark GPCRs and Mitochondrial Transport

Ketone-body Dependent Post Translational Modifications

Closing Remarks

2025

Session 1: Metabolism in Human Health and Disease

Welcoming remarks

Mitochondrial Dynamics and Cardiometabolic Disease

Insulin Regulation of Bile Acid Physiology

Metformin Intervention in STAMPEDE

Human Steroid Metabolism Phenotypes

Muscle Metabolic Alterations with Physical Activity and Disuse

Session 2: Dietary Interventions to Combat Metabolic Dysfunction

Dietary Interventions and Nutrient Availability in Cancer Progression

Nutritional Strategies to Improve Metabolic Health and Potentially Longevity

A ketone shunt generates anti-obesity ketone metabolites

Session 3: Approaches for Studying Human Metabolism

Spatial Imaging of Metabolites Paired with Transcript and Peptide Imaging

Toward Single Cell Resolution for Mass Spectrometry Metabolite Imaging

Physiomimetic Microsystems for Studying Metabolism

2024

Welcoming Remarks

Session 1: Normal Metabolism and the Diversity of Human Metabolic Phenotypes

Overarching Perspectives on Metabolism

Opportunities for Studying Diverse Populations in Miami

Prostate Cancer and Genetic Ancestry in Jamaican Men

Session 2: What Happens When Metabolism Goes Awry?

Metabolic Adverse Effects of Hormonal Therapy

Metabolic Stress in Men Training for the Special Forces

Effects of Stress and Hormonal Therapy on Steroid Metabolism

Session 3: How Can We Favorably Modify Human Metabolism?

Time Restricted Eating as a Method to Optimize Metabolism

Mechanistic Consequences of Amino Acid Deprivation on Translation

Dietary Interventions with Cancer Therapy

Regulation of an Exercise-Inducible Appetite Suppressant

Session 4: Approaches for the Study of Human Metabolism

Spatial Resolution of Carbohydrate Metabolism

Imaging Metabolic Dependence of the Myc Oncogene

Molecular Mapping at Cellular Resolution with Multimodal Imaging Mass Spectrometry

Emerging Approaches for the Study of Metabolomics in Humans