July 9, 2025
Guest: Thomas Malek, Ph.D.
Listen Time: 29m 6s
Can a lab-developed protein offer a long-term solution for treating autoimmune diseases?
Autoimmune diseases lead to devastating, and sometimes deadly, health outcomes for millions of people worldwide, yet they remain some of the most difficult conditions to treat. These diseases, like lupus and Type 1 diabetes, occur when the immune system mistakenly attacks healthy tissues.
Current therapies often rely on broad immunosuppressants, which can weaken the entire immune system and lead to serious side effects. What patients need isn’t a total shutdown of immunity: It’s a reset.
In this episode of “Inside U Miami Medicine,” Thomas Malek, Ph.D., a preeminent immunologist, shares how his groundbreaking work is helping to redefine what that “reset” could look like. With a research career spanning four decades, Dr. Malek has zeroed in on a powerful immune modulator: a novel fusion protein called IL-2/CD25.
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