The absence of suitable biomarkers for amyotrophic lateral sclerosis (ALS) poses a major obstacle to therapy development. For this reason, the discovery and validation of potential disease progression and pharmacodynamic biomarkers has been one of the top priorities in ALS research.
In a groundbreaking study published February 22 in the journal Neurology, researchers with the University of Miami Miller School of Medicine and Flinders University in Australia have identified concentrations of p75ECD, the extracellular domain on the common neurotrophin receptor p75, as the first biological fluid-based biomarker for ALS progression.
In a comprehensive new review article in Nature Biotechnology, Claes Wahlestedt, M.D., Ph.D., professor of psychiatry and behavioral sciences, and associate dean for therapeutic innovation, at the University of Miami Miller School of Medicine, describes the entire field of oligonucleotide therapeutics as it relates to a wide variety of disorders of the central nervous system.
Hope for some people with epileptic seizures not controlled by medication comes in the form of a new minimally invasive technique called laser interstitial thermal therapy. And the University of Miami Health System’s Epilepsy Center is the only facility offering this treatment option in South Florida.
In January, Hall of Fame drag racer Darrell Gwynn was in Scottsdale, Ariz., for the famed Barrett-Jackson Auction. There he sold a 1964 Ford Galaxie 500XL custom hardtop, which had been donated by a friend. The proceeds of the car auction supported a wheelchair donation to Derik Hanson, a local child who was paralyzed by Transverse Myelitis at the age of 6 months, and paralysis research at The Miami Project to Cure Paralysis.
Four pioneers of community health care in Miami came to the Mailman Center for Child Development at the University of Miami Miller School of Medicine Wednesday night to share lessons from the past and inspiration for the future at a Black History Month roundtable.
When George L. Sanders, M.D. ’69, came to South Florida to study at the University of Miami School of Medicine in 1965, the shadow of racism was never far away. The school’s only African-American student at the time, he was refused admittance to most of the medical societies, and he was once barred from entering an apartment complex where his classmates had arranged a study session.