Skip to Main Content

Contact

Primary Investigator

Juan Domínguez-Bendala, Ph.D.

Mailing Address

Research Professor of Surgery
Diabetes Research Institute
University of Miami Miller School of Medicine
1450 NW 10th Ave
Miami, FL 33136

Lab: 305-243-4092 Email

Postdoctoral Fellow, Diabetes Research Institute, University Of Miami

A postdoctoral associate position is available at the Diabetes Research Institute of the University of Miami. The main lines of research in the Beta Cell Regeneration Lab revolve around the development of regenerative strategies for type 1 diabetes, including stem cell differentiation into insulin-producing β-cells and islet regeneration. In particular, our current research is focused on the induction of human pancreatic ductal BMP-responsive progenitor cells, which we have identified and characterized by lineage tracing (Klein et al., Diabetes, 2015; Qadir et al., Cell Reports, 2018); single-cell RNAseq and transplantation of sorted populations (Qadir et al., PNAS, 2020); and organotypic culture (human pancreatic slices) techniques (Qadir et al., Nature Comms, 2020). Our seminal contribution to the development of the latter has enabled for the first time the real-time monitoring of β-cell regeneration in an in vitro setting that resembles the native organ. Our research pipeline is expected to help us realize the full potential of single-cell transcriptomics to unveil dynamic biological processes, model human pancreatic disease, and, ultimately, enable the development of regenerative therapies for diabetes.

Job Duties

  • Work on an NIH-funded project involving longitudinal single-cell analytical techniques in state-of-the-art human pancreatic slice (HPS)-based system.
  • Develop and execute original research and possess a high motivation to drive and conduct research.

Minimum Qualifications

  • M.D. or Ph.D. in Basic Science, Health Science, or a related field.

Preferred Qualifications

  • Demonstrate a solid publication record and evidence of excellent skills/experience in one or more of the following areas: bioinformatics, single-cell RNAseq analysis, pancreatic tissue culture.

Contact:

  • Juan Domínguez-Bendala, PhD. Professor of Surgery, Diabetes Research Institute, University of Miami
    Email: jdominguez2@med.miami.edu