Obstetrics, Gynecology and Reproductive Sciences.
Associate Director, Diversity, Equity and Inclusion
BiographyDr. Sophia George, PhD is an Associate Professor appointment in the Division of Gynecological Oncology within the Department of Obstetrics and Gynecology at the Leonard M. Miller School of Medicine and a full member of the Sylvester Comprehensive Cancer Center. She is a Department of Defense Ovarian Cancer Academy Awardee. Dr. George is a native of the Caribbean and is part of a team of multi-disciplinary team who studies the incidence of Hereditary Breast and Ovarian Cancer syndrome genetic mutations in Afro-Caribbean nationals.
Education & Training
Post Graduate Training
Honors & Awards
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Research InterestsHer research interests lie in understanding the effects of inherited genetic mutations on the fallopian tube and breast epithelia and their involvement in high-grade serous and triple-negative breast cancer development. She studies homologous recombination deficiency (HRD), DNA damage repair response, the enzymes and pathways responsible for sensing in the context of women’s cancers. Specifically, in the laboratory Dr. George, studies fallopian tube epithelia from women deemed to be at a high-risk for developing breast and/or ovarian cancer and breast and ovarian tumors from women with a germline mutation BRCA mutation carriers. Her work with others has found that the menstrual cycle (hormones), inflammation, parity and obesity, all influence the development of ovarian cancer.
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