Dr. Zhai’s research is focused on understanding the genetic and molecular mechanisms of neural degeneration and protection in the context of both common and rare neurological disorders. Her group uses a ‘Drosophila - mammalian two-model’ systems, to identify genetic components in Drosophila and characterize the cellular mechanisms in mammalian cells. Her group discovered and characterized one of the most robust neuroprotective factors that has broad therapeutic potential against several neurodegenerative diseases including Alzheimer’s and Huntington’s disease. At the same time, her group has established numerous genetic models for rare diseases and carried out mechanistic analysis of neurological phenotypes that have led to successful therapies in human patients.
Publications
Grants & Sponsored Research
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Copyrights & Patents
METHOD OF TREATING POLYAMINE IMBALANCE-RELATED DISORDERS
235827380224, 2022
NEW VIRAL DNA CONSTRUCTS EXPRESSING VARIOUS FLUORESCENT PROTEINS:PLV-EGFP-MITOGFP
235827382272, 2022
NEW VIRAL DNA CONSTRUCTS EXPRESSING VARIOUS FLUORESCENT PROTEINS:PLV-MITODSRED
235827384320, 2022
TREATMENT AND DETECTION OF INHERITED NEUROPATHIES AND ASSOCIATED DISORDERS
