| Perforin 2 Proteins as a Novel Antibacterial therapy |
| This invention relates to the fields of antibiotics, anti-cancer agents and drug discovery. More specifically, it relates to a compound useful in activating the body’s natural defenses to both infections and tumors. |
| The incidences of serious bacterial infections are increasing at home and in hospitals due to the development of antibiotic resistance. Furthermore, there are certain bacteria such as those causing tuberculosis that are naturally resistant to most antibiotics. For biological reasons alone, there is an urgent need to discover novel antibacterial agents. Antibiotics, many of which have patents that will expire in the next few years, are currently a multi billion dollar industry. |
| This is a unique antibacterial approach in that it will not lose efficacy due to the development of resistance. |
| Vadim Deyev and Eckhard R. Podack |