UM Researchers Find HIV Patients Have Higher Prevalence of Metabolic Syndrome
Researchers at the University of Miami Miller School of Medicine have discovered that HIV-infected patients being treated with antiretroviral therapy have higher incidences of Metabolic Syndrome than in previously reported HIV cohorts. Lead author Eduard Tiozzo, Ph.D., an American Heart Association Fellow, found that one in three participants in the Healthy Living for Better Days program, an exercise training and nutrition education community program for HIV patients at the UHealth Fitness and Wellness Center, had had Metabolic SyndromeS (MetS).
MetS is diagnosed when patients exhibit three or more of the following features: abdominal obesity, hypertriglyceridemia, low levels of high-density cholesterol, insulin resistance, and hypertension. The study findings, published in Diabetology and Metabolic Syndrome, reported that the higher prevalence of MetS was “driven by a high rate of abdominal obesity and hypertension,” with the most contributing factors being elevated hemoglobin A1C and high consumption of carbohydrates, primarily in the forms of naturally occurring and added sugars.
“Our study provides a baseline for future studies to more conclusively determine if MetS is a more disease dependent or lifestyle dependent constellation of symptoms in HIV patients,” said Tiozzo, an exercise physiologist and junior faculty in the Departments of Psychiatry and Behavioral Sciences and Neurology.