Lymphoma Physician-Researcher at Sylvester Awarded Key Bridge Grant from ASH

Izidore Lossos, M.D., leader of the Lymphoma Program at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, has received a prestigious Bridge Grant from the American Society of Hematology (ASH), the world’s largest professional society focused on the causes and treatments of blood disorders.

In his research, Lossos, professor of medicine at the Miller School in the Division of Hematology/Oncology, has been studying the function of a recently cloned gene, HGAL, in lymphoma. The HGAL protein prevents lymphoma dissemination and regulates B-cell receptor signaling. His goal is to further study the function of HGAL in these two areas of lymphoma genetics.

“We believe this protein can provide us with a better understanding of why some lymphomas behave differently than others,” said Lossos. “From that information, it can become a useful prognostic for patients. I’m grateful to ASH for funding that can help us learn more.”

In an effort to preserve hematology research projects as the National Institutes of Health was restricting federal funding, ASH committed $9 million in 2012 to create the ASH Bridge Grant program. Each one-year, $150,000 award is designed to “bridge” recipients between NIH grants, allowing them to continue their critical work in the field of hematology.

Lossos is one of 12 researchers to receive an ASH Bridge Grant this year. For the last 10 years, he has received NIH funding.

“Izidore’s clinical and scientific work in lymphoma has distinguished him as a recognized leader in the field of lymphoma,” said Stephen D. Nimer, M.D., Director of Sylvester Comprehensive Cancer Center. “This funding recognition from the premier organization for blood disorders is further validation of his research.”

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