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12.01.2010

Cardiovascular Chief Publishes Heart Attack Study

Mauro Moscucci, M.D., M.B.A., professor and senior vice chair of the Department of Medicine and chief of the Cardiovascular Division, published an article on the treatment of patients with myocardial infarction in the November 8 issue of the Archives of Internal Medicine.

The study, conducted with colleagues from the University of Michigan, examines trends in door-to-balloon (DTB) time and mortality in myocardial infarction patients undergoing percutaneous coronary intervention. A door-to-balloon time (defined as the interval between the patient’s arrival in the emergency room and the insertion of a balloon to open a blocked coronary artery) of less than 90 minutes had been previously associated with improved survival. But the study found that, while there has been a dramatic reduction in median DTB time below the 90-minute gold standard and increased compliance with the related national guidelines, in-hospital mortality was unchanged over the study period.

These results suggest that a successful implementation of efforts to reduce DTB time has not resulted in the expected survival benefit. According to Dr. Moscucci, it remains to be seen whether further reducing DTB to less than 60 minutes, coupled with a campaign to educate patients with chest pain to seek medical attention without delay, will eventually result in improved survival for patients with myocardial infarction. To read the full text of the article, visit the Archives of Internal Medicine.

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