Breast Cancer Researcher Ready to Ride in DCC

Marc E. Lippman, M.D., is looking forward to riding in the Dolphins Cancer Challenge (DCC), on Saturday, February 20, at Sun Life Stadium. As one of the nation’s leading breast cancer researchers, Lippman understands the importance of raising funds for the Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine.

“We are studying the factors in a woman’s life that can lead to metastatic breast cancer and its recurrence,” says Lippman, who is Sylvester’s deputy director, and the Miller Professor of Medicine at the Miller School. “Many people don’t realize that more women die of breast cancer after a five-year remission than during those first years after treatment,” he says. “That’s because the cancer cells can hide from the body’s immune system for many years, until depression, obesity or other conditions affect a woman’s health.”

Metastatic breast cancer is the most difficult form of breast cancer to treat with the highest morbidity rates, adds Lippman, who leads a team of physician-scientists at Sylvester who are probing the connections among breast cancer tumors, inflammation and the health of the body’s immune system.

“We have found similar profiles of cytokines, proteins released by the immune system, in women with obesity, depression and breast cancer,” he says. “That’s an important finding, because most forms of metastatic disease recur months or years after the original diagnosis and initial treatments, and are likely increased by these inflammatory cytokines. Now, we are partnering with other Miller School departments to launch a major clinical trial for breast cancer patients with depression to see if we can reduce the likelihood of recurrence.”

An active cyclist who has participated regularly in the annual DCC fundraising campaign, Lippman urges University of Miami faculty, staff, students, alumni, friends and family members to take part in DCC VI, which includes a 5K walk and run, and the option of participating as a virtual rider. “You can help our Sylvester researchers save lives by advancing our understanding of breast cancer,” he says. “I invite you to DCC with me.”

To learn more, please visit Dolphins Cancer Challenge.

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