e-Update: News for University of Miami Miller School of Medicine Faculty and Staff

Up Front

Members of the Miami Regional Coordinating Center are, from left, Italo Linfante, M.D., Baptist Health South Florida; Sayed Naqvi, M.D., Miami Children’s Hospital; Dileep R. Yavagal, M.D., Miller School; Bonnie E. Levin, Ph.D., Miller School; Miguel Perez-Pinzon, Ph.D., Miller School; Dushyantha Jayaweera, M.D., Miller School; Sebastian Koch, M.D., Miller School; Amy K. Starosciak, Ph.D., Baptist Health South Florida; Iszet Campo-Bustillo, M.P.H., CCRP, Miller School; Jose Romano, M.D., Miller School; Petra Kaufmann, M.D., MSc, National Institutes of Health; Ralph L. Sacco, M.D., M.S., Miller School; James N. Goldenberg, M.D., CPI, JFK Medical Center; Gillian Gordon-Perue, M.D., Jackson Memorial Hospital/Miller School; Ofelia A. Alvarez, M.D., Miller School; David Kushner, M.D., UM Rehabilitation Program at HealthSouth Miami; Amanda Coltes-Rojas, CIP, UM Human Subjects Research Office; and Jacob L. McCauley, Ph.D., Miller School.

Members of the Miami Regional Coordinating Center are, from left, Italo Linfante, M.D., Baptist Health South Florida; Sayed Naqvi, M.D., Miami Children’s Hospital; Dileep R. Yavagal, M.D., Miller School; Bonnie E. Levin, Ph.D., Miller School; Miguel Perez-Pinzon, Ph.D., Miller School; Dushyantha Jayaweera, M.D., Miller School; Sebastian Koch, M.D., Miller School; Amy K. Starosciak, Ph.D., Baptist Health South Florida; Iszet Campo-Bustillo, M.P.H., CCRP, Miller School; Jose Romano, M.D., Miller School; Petra Kaufmann, M.D., MSc, National Institutes of Health; Ralph L. Sacco, M.D., M.S., Miller School; James N. Goldenberg, M.D., CPI, JFK Medical Center; Gillian Gordon-Perue, M.D., Jackson Memorial Hospital/Miller School; Ofelia A. Alvarez, M.D., Miller School; David Kushner, M.D., UM Rehabilitation Program at HealthSouth Miami; Amanda Coltes-Rojas, CIP, UM Human Subjects Research Office; and Jacob L. McCauley, Ph.D., Miller School.

Miller School Leads Miami Arm of NIH Stroke Network Set to Revolutionize Clinical Research

The University of Miami Miller School of Medicine has been named part of a national stroke network established by the National Institutes of Health to more quickly translate research discoveries to patients. Recognized for its excellence in the field of stroke prevention and treatment, the Miller School will lead the Miami Regional Coordinating Center (RCC), one of 25 regional stroke centers working with nearby satellite facilities around the nation. The centers will have teams of researchers representing every medical specialty needed for stroke care, addressing the three prongs of stroke research: prevention, treatment and recovery.

The Miami RCC, led by Jose G. Romano, M.D., professor of neurology and Chief of the Stroke Division, and Ralph L. Sacco, M.D., M.S., professor and chair of neurology and Olemberg Family Chair in Neurological Disorders, will provide a robust infrastructure to foster clinical trials, leverage local and regional resources to benefit the Stroke Trials Network, and train the next generation of researchers.

Read more about StrokeNet »

More News

Stephen D. Nimer, M.D.

Stephen D. Nimer, M.D.

Sylvester Study Finds Potential New Approach to Treating Leukemia

A Miller School research study has found a potential new approach to halting the growth of acute myelogenous leukemia (AML), a deadly blood-borne cancer in adults and children.

“We found that blocking an enzyme called PRMT4 caused leukemia cells to die,” said Stephen D. Nimer, M.D., Director of the Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine. “This study indicates that targeting PRMT4 holds potential as a novel therapy for AML.”

Nimer’s study, “PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex,” was published December 12 in the journal Cell Reports. It is the latest in a series of studies led by Nimer probing the genetic and cellular processes that lead to AML, and reflects a series of collaborations established among scientists at UM, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, University of Alabama, Birmingham, and other institutions.

Read more about the study »

Ramiro E. Verdun, Ph.D.

Ramiro E. Verdun, Ph.D.

Study Identifies DNA Repair Mechanism that Could Lead to Tumor-Targeted Treatment Strategies

In a study led by Ramiro E. Verdun, Ph.D., assistant professor of medicine in the Division of Gerontology and Geriatric Medicine, researchers have uncovered a mechanism to repair different types of DNA double-strand breaks, highly toxic lesions that, if left unrepaired, can produce a permanent arrest of cell division or cell death. These findings open the door to establishing new tumor-targeted treatment strategies involving induction of DNA lesions, specifically during chemo- and radiotherapy.

Published December 1 in The Journal of Immunology, the study found that two DNA repair pathways believed to compete during the DNA recombination process — classical non-homologous end-joining and a C-terminal binding protein interacting protein (CtIP)-dependent, alternative end-joining pathway — are simultaneously active during class-switch recombination (CSR), and, rather than competing, they more ably repair different types of double-strand breaks.

Read more about the study »

Jeffrey P. Brosco, M.D., Ph.D.

Jeffrey P. Brosco, M.D., Ph.D.

Pediatrician Teams Up with Historian to Shed Light on Enigma of PKU Screening

An article about a new book co-authored by Jeffrey P. Brosco, M.D., Ph.D., professor of clinical pediatrics and Associate Director of the Mailman Center for Child Development, was the “Monthly Feature” in the December issue of the prestigious journal Pediatrics.

In the article, adapted from their book The PKU Paradox: A Short History of a Genetic Disease, Brosco and historian Diane B. Paul, Ph.D., discuss the politics of genetic testing in newborns and how a simple screening test for phenylketonuria (PKU) became the prototype for universal newborn screening programs.

Read more about the book and feature article »

Julia Telischi introduces Debbie School students to their new instruments.

Julia Telischi introduces Debbie School students to their new instruments.

Math-Minded Student Brings “Musically Minded” Therapy to Debbie School

Thanks to one high school student’s compassion, determination and gift for math, preschool classrooms at the Debbie School, a division of the Mailman Center for Child Development, are now equipped with keyboard pianos, bongo drums, xylophones, diatonic bells, headphones and other resources teachers can use to provide music therapy to students with hearing impairments.

A senior at Ransom Everglades School in Miami, 17-year-old Julia Telischi has a lot of second-hand knowledge about growing up with hearing loss. Her father Fred Telischi, M.D., professor and Chair of Otolaryngology, has helped hundreds of children gain the gift of hearing. So, to earn her Girl Scout Gold Award, Julia spent two years as a math tutor to raise the necessary funds to equip Debbie School classrooms with instruments and other resources children can use to improve their listening and communication skills — while having fun.

Read more about the project »

UM to Host Inaugural Cancer Symposium: “Cancer Prevention and Treatment”

Faculty, students, fellows and residents are invited to submit abstracts for “Cancer Prevention and Treatment,” a symposium hosted by Sylvester Comprehensive Cancer Center and the Department of Urology, on Friday, January 24, from 10 a.m. to 2:45 p.m. The deadline for abstract submission is Monday, January 6.

The inaugural Cancer Symposium, sponsored by generous support from the Dr. Edwin Cevallos Family and Dr. Helen and David Wei, will begin in the Lois Pope LIFE Center, seventh-floor auditorium with several distinguished lectures, including “Cancer Chemoprevention and Treatment,” “Cancer Stemness: Quiet Cells Need Knocking Down a Notch,” and “Can Prostate Cancer Be Prevented?”

Read more about the symposium and RSVP »

Buoniconti Fund to Cure Paralysis 4th Annual Holiday Bazaar

The Buoniconti Fund to Cure Paralysis will host its 4th Annual Holiday Bazaar on Tuesday, December 17, in front of the Lois Pope LIFE Center from 9 a.m. to 3 p.m.

Avoid the long lines, do your holiday shopping and get great discounts for a great cause. The Bazaar will feature holiday gifts, accessories, travel, Kidz Korner, jewelry, watches, home goods, and much more. For more information, call 305-243-2267.

Register Now for the 4th Annual Therapeutic Hypothermia and Temperature Symposium

Sponsored by the Miller School and presented by the Department of Neurological Surgery, the 4th Annual “Therapeutic Hypothermia and Temperature Management: Current and Future” symposium will be held March 6-7 from 7 a.m. to 5 p.m. at the Marriott Biscayne Bay, 1633 North Bayshore Drive, Miami.

Read more about the symposium »

Register Now for Neurology Update and Stroke Intensive 2014

Sponsored by the Miller School and hosted by the Department of Neurology, the symposium “Neurology Update and Stroke Intensive 2014” will be held February 6-8 from 7 a.m. to 4 p.m. at the Mayfair Hotel, 3000 Florida Avenue, Miami. The symposium is designed to provide clinicians with the most recent developments in the diagnosis and management of neurological disorders, including stroke. It will cover the latest advances in the different fields of neurology and neuroscience, including epilepsy, sleep disorders, multiple sclerosis, movement disorders and neuromuscular diseases, all of which are critical in solving clinical problems, diagnosing and treating patients and improving the quality of patient care.

Read more about the symposium »

Department of Ophthalmology to Host Two-Day Mass Spectrometry Seminar

The Department of Ophthalmology invites you to attend a two-day mass spectrometry seminar from 9 a.m. to 4 p.m. on Thursday, January 9, and Friday, January 10, at Bascom Palmer Eye Institute, Jose Berrocal Auditorium.

Read more about the seminar »

A Note on UHealth and the Health Insurance Marketplace

Having recently completed our 2014 Benefits Open Enrollment, the University of Miami continues to offer employer-sponsored healthcare to all eligible employees. Faculty, staff and their family members who are eligible for the UM/Aetna plans need not look to the Health Insurance Marketplace for health coverage.

For many others in our community, including friends and extended family members, the launch of the Affordable Care Act and its new Health Insurance Marketplace poses many questions about choosing the right health coverage. Members of the community who want access to UHealth’s top-ranked physicians and state-of-the-art facilities should be aware that UHealth has relationships with several insurance providers.

Read more about UHealth and the Health Insurance Marketplace insurance providers »

Miller School Newsletter Holiday Schedule

This is the last issue of e-Update for 2014. The newsletter will not be published on Tuesday, December 23, or Tuesday, December 30.

Also, please note that the deadline for the January issue of MED is Tuesday, December 30, at noon.

Happy Holidays!