A long-time Miller School researcher, who has dedicated her career to studying the mechanisms that fuel cancers of the prostate and bladder, is now studying a promising drug combination to combat kidney cancer. More than one-third of patients with kidney cancer develop metastasis despite treatment, and less than 10 percent of them survive beyond five years.
Vinata B. Lokeshwar, Ph.D., professor of urology and cell biology and Director of Pilot Studies at the Miami Clinical and Translational Science Institute (CTSI), was awarded a five-year, $1.7 million grant from the National Institutes of Health to test a combination of sorafenib, a drug already approved for kidney cancer, with the dietary supplement hymecromone in pre-clinical models. The drug combination was shown to eliminate kidney tumors in mice without toxicity, and if successful in humans could be the first to prevent the cancer from metastasizing.
Robert C. Hendel, M.D., professor of medicine and radiology, has been named interim Chief of the Cardiovascular Division at the University of Miami Miller School of Medicine. Before this appointment, he was the Associate Chief of Clinical Cardiology, Director of the Cardiac Care Unit and Director of Cardiac Imaging at the Miller School
A newly opened outpatient facility in Deering Plaza is providing South Dade families with direct, convenient access to UHealth pediatric specialists. UHealth Pediatric Specialists South, located in an office building adjacent to Jackson South Community Hospital, serves patients from newborns to age 21.
A collaborative Miller School study led by Priyamvada Rai, Ph.D., assistant professor of medicine in the Division of Gerontology and Geriatric Medicine, describes a novel therapeutic target in RAS-driven lung cancer, a common but untreatable carcinoma. The study, published in Oncogene describes a critical role for MTH1, a protein which sanitizes oxidized DNA precursors, in facilitating tumor formation by activated KRAS.
Mohammad Jahanzeb, M.D., Medical Director of Sylvester Comprehensive Cancer Center at Deerfield Beach, has been appointed Chair-Elect of the American Society of Clinical Oncology’s Quality Oncology Practice Initiative (QOPI®) Steering Group Committee.
Thanks to a generous $500,000 gift from the Pediatric Epilepsy Research Foundation (PERF), new financial incentives will soon be in place in perpetuity for students at the Miller School of Medicine. The not-for-profit foundation, which is led by Miller School alumnus Roy Elterman, M.D. ’74, is establishing two scholarships to assist students for generations to come.